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165 Biotransformation pathways may generate active metabolites that enhance or reduce efficacy or cause off-target toxicity

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Si vous ressentez des symptmes tels qu'une ruption cutane, des dmangeaisons ou des difficults respiratoires, consultez immdiatement un mdecin

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The lid domain and glycine-rich loop are critical for ATP binding, which triggers major shifts in their conformations (Galant et al., In the structures of human and yeast GS, two alanine residues form van der Waals contacts with the glycine moiety of glutathione (Polekhina et al., These structure/function studies established the basis of glutathione versus homoglutathione specificity, but it remains unclear how other glutathione analogs are formed in different plants

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