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Gene expression profiling showed upregulation of fatty acid oxidation genes including CPT1A and ACADM, indicating a metabolic shift from lipid storage toward lipid utilization
Without barriers such as digestion, the body absorbs 15-97% of the injected B12, making injections much more efficient at raising blood levels quickly even if the pill dose is higher
Two are FDA-approved specifically as injectable weight loss medications: Saxenda (liraglutide) approved in 2014, injected once daily
Intramuscular injection may occasionally cause skin rash, itching, diarrhea, and allergic asthma
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