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Lipid-based vesicles modified with lactoferrin or cationic lipids further exploit disrupted mucosal barriers to enhance epithelial penetration [399]
NEJM , 2023
Systematic reviews and meta-analyses of randomized trials have further confirmed that while GLP-1RAs lower body weight and fat mass significantly, they do not appear to exert an independent detrimental effect on skeletal muscle index beyond expected proportional reductions [25]
The people who explored alternative weight management peptides or weight loss stacks alongside exercise had better long-term outcomes than those who relied on any single intervention alone
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