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Your body creates energy inside your cells specifically in structures called mitochondria
When the oxidative metabolism in mitochondria is abnormal, the electronic leakage increases the uncoupling of oxidative phosphorylation, resulting in the production of oxygen free radicals which may induce LPO reactions (Figure 1) [70]
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Subsequent trials, including AWARD-10 and SUSTAIN-9, further confirmed the efficacy of intensification strategies, demonstrating meaningful improvements in glycemic control and body weight when one class is added to the other [31, 32]
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