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(1) Both these findings on chronic and acute action of AOD 9604 suggested that while enhanced beta(3)-AR expression may have played a role in the chronic action of the compound, beta(3)-AR might not be the sole arbiter in this reaction
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At the molecular level, AOD-9604 may act on beta-3 adrenergic receptors in adipose tissue, promoting fat oxidation without stimulating IGF-1 production
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