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Nmeth and Boda measured a xanthine oxidase activity index and a GSSG/GSH ratio in infants and children with septic shock and showed that these indices were significantly correlated with each other, with severity of illness scores (PRISM), and were increased in patients in a proinflammatory state (26)
Packer 2025 in NEJM (PMID 39555826) reported on heart failure with preserved ejection fraction (SUMMIT), with tirzepatide producing improvements in patient-reported symptom burden and quality-of-life scores
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