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doi: 10.1038/sj.ijo.0801740 84 StierHVosEKenleyD
For instance, investigations into defective immunometabolism in CF macrophages have utilized the Seahorse Extracellular Flux analyzer, revealing impaired oxygen consumption, both at baseline and following infection with challenging pathogens like Burkholderia cenocepacia ( F508del/F508del , can be remarkably normalized by triple CFTR modulator therapy through mechanisms involving calcium (Wisniewski et al., 2025)
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