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Dietary modifications can substantially reduce digestive discomfort: Consume smaller, more frequent meals (5-6 times daily) rather than three large meals Choose bland, low-fat foods during the initial treatment period and after dose increases Avoid high-fat, fried, or heavily spiced foods that delay gastric emptying further Stay well-hydrated with small, frequent sips of water throughout the day Limit carbonated beverages and alcohol, which may exacerbate nausea and bloating Eat slowly and chew food thoroughly to reduce the volume of food in the stomach Avoid or limit medications that further slow gastric emptying (opioids, anticholinergics) Pharmacological interventions may be appropriate for patients with persistent symptoms despite dietary modifications

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Your healthcare team can adjust your treatment plan, provide supportive management for side effects, or consider alternative therapies if GLP-1 receptor agonists are not suitable for you

Pregnant or breastfeeding women should also not take semaglutide due to unknown risks it may pose on the growing fetus