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They gave a group of people the drug and a group of people the placebo and then wrote up the results

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This creates a coverage gap for patients who: Don't meet the BMI or comorbidity criteria for Wegovy Are denied prior authorization for Wegovy and don't want to appeal Want to start treatment immediately without waiting for step therapy completion Prefer a lower dose than the FDA-approved products offer For these patients, compounded semaglutide is available only as an out-of-pocket expense

Caution and monitoring of blood pressure standing vs sitting are reasonable