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Limitations of Current Evidence Several significant limitations in the current evidence base warrant acknowledgment: Population Diversity : Most major trials have been conducted in predominantly white, well-resourced populations, potentially limiting generalizability to more diverse demographic groups where obesity prevalence is often highest

Geographic Availability Not available in AL, AK, AR, HI, LA, MS, MO, SC, WV Clinical Oversight and Safety Prescribing is managed by licensed NPs or PAs under a physician-led team, including a DO chief medical officer and an MD endocrinologist

While adequate folate intake appears protective before malignant change occurs, excessive folic acid exposure, particularly in susceptible individuals with reduced DHFR activity, may not always be desirable

This post is full of tips to help you keep some weight off when youre on a break from your treatment