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doi: 10.1016/j.etap.2016.09.023 59
Achieved dose-dependent weight reductions, with lower doses producing steady, moderate loss Experienced consistent weight improvements whether they had obesity alone or obesity with type 2 diabetes This level of weight loss is similar to early GLP-1 injection trials but delivered through a once-daily pill
Fasting and Protein Cycling Short periods of fasting or reduced protein intake can stimulate endogenous growth hormone release
At 48 weeks, the 12 mg retatrutide group lost a mean of 24.2% of body weight, with 83% achieving at least 15% weight loss
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