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For lean patients with less than 1/2 inch of subcutaneous fat, a 45-degree angle with a 5/8-inch needle penetrates too deep and hits muscle

A 2018 systematic review and meta-analysis identified 20 randomized controlled trials (published between 2007 and 2017) that examined the effect of supplemental lipoic acid on markers of glucose utilization in 1,245 subjects with metabolic disorders (not limited to type 2 diabetes) (60)

Glutathione, composed of three amino acidscysteine, glutamate, and glycinefunctions as a key player in cellular processes, helping to neutralize free radicals, detoxify harmful substances, and support overall immune function

300 (1), F167-176 (2011)