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Yes, modest heart rate increases of 2-4 beats per minute are documented in clinical trials and noted in the FDA prescribing information
Monitoring: Metabolic: Monitor for signs/symptoms of hypoglycemia GI: Monitor for signs/symptoms of pancreatitis after starting therapy Renal: Monitor renal function in patients with renal dysfunction reporting severe adverse GI reactions (especially when starting or escalating doses) Patient advice: Read the US FDA-approved patient labeling (Medication Guide and Instructions for Use)
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A systematic review of the antidepressant effects of glucagon-like peptide 1 (GLP-1) functional agonists: further link between metabolism and psychopathology: special Section on Translational and Neuroscience Studies in Affective Disorders
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