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The pre-conception window matters because the final maturation of an egg takes around 85-90 days and spermatogenesis is approximately 2-3 months, so you need a 3-month runway before supplements influence any given cycle
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10.1016/j.expneurol.2020.113585 513 ZhaoL.ZhangF.DingX.WuG.LamY
17- Estradiol Regulates Proglucagon-Derived Peptide Secretion in Mouse and Human - and L Cells
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