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Aug 2018;34(8):684-688
The precise mechanisms leading to its anticancer effects are not clearly established, although multiple mechanisms affecting enzyme activity, transcription factors, cellular signalling and mitochondrial functions have been proposed
The activated Akt subsequently modulates many downstream effector proteins associated in cell survival, proliferation, metabolism, and glucose transport (Fletcher et al
Another 5% to 10% were low responders, losing less than 10% despite completing the full protocol
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