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Schmidt AM, Hori O, Chen JX, Li JF, Crandall J, Zhang J, Cao R, Yan SD, Brett J, Stern D (1995) Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice

In the Phase 3 TRIUMPH-4 trial, participants taking 12mg of retatrutide lost an average of 28.7% of their body weight over 68 weeks