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Increased TMAO levels are caused by lower clearance and increased synthesis as a result of gut dysbiosis, a weakened intestinal barrier, and increased hepatic enzyme activity
Timeline expectations Drug development typically takes 10-15 years from discovery to approval
Following recommended dosing guidelines and cycle durations can significantly reduce the likelihood of experiencing this side effect
What matters is whether complaints exist, whether the same issues keep popping up, and whether the clinic responds and resolves them
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