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Mounjaro injection (tirzepatide 15 mg, weekly): around 20% average weight loss over 72 weeks in SURMOUNT-1, the highest figure in the class so far
GLP-1 receptor agonists stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning they promote insulin release primarily when blood glucose levels are elevated
Nanoscale designed formulations have been extensively studied in recent decades for compounds with high lipophilicity, providing significant advantages such as improving solubility, optimising their release profiles and increasing bioavailability, and have achieved important successes
This finding suggests that overall rates of use in the population have held steady over the past two years
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