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The dose is escalated gradually from 0.25 mg to 0.5 mg, then to 1 mg, and where clinically necessary, to 2 mg always under the guidance of a healthcare professional
Participants were randomized in a 1:1:1:1 ratio to receive once-weekly retatrutide at doses of 4 mg, 9 mg, 12 mg, or placebo for 80 weeks
Last update: July 15, 2026 Est
see panel d inset for the culture design)
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![β-Ala28]-Tirzepatide](https://www.daicelpharmastandards.com/wp-content/uploads/2024/02/dcti-d-338.png)
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