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No withdrawal symptoms occur, but patients often notice decreased energy and sleep quality within weeks of discontinuation

however, mitochondrial NAD/NADH ratios are maintained at much lower levels

Participants did not report subjective symptoms such as palpitations or chest discomfort at a higher frequency than placebo, and discontinuations due to heart rate were not a major feature of the trials

However, you must disclose your complete antidepressant regimen to PlexusDx during your initial consultation so our team can confirm no individual risk factors apply and monitor you during the first few weeks of treatment