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Regulatory uncertainty limits its medical positioning, currently placing it in the grey zone of experimental peptides These limitations make clinical endorsement premature, especially in regulated health systems or for medical-grade use
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Consistency of findings from between-trial and within-trial comparisons, formal statistical testing verifying the absence of a subgroup effect and the similarity of baseline cardiovascular risk across different cardiovascular risk categories between individual CVOTs despite the use of seemingly different enrolment criteria suggest the benefits of the use of SGLT2i or GLP-1 RA in people with type 2 diabetes and established CVD and in those at high cardiovascular and/or kidney risk [142, 253]
collagen and aging: a scientific perspective
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