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Physiol Rev 87(4):14091439 Holst JJ (2019) Long-acting glucagon-like peptide-1 receptor agoniststatus December 2018
Independent testing and MHRA enforcement activity (including Operation Pangea) have found that many such products contain incorrect concentrations, impurities, or in some cases entirely different substances to those labelled
Additionally, about 6.8% of patients discontinue GLP-1 treatment due to side effects, primarily gastrointestinal issues
The 5mg/5mg ratio provides balanced stimulation through both pathways
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