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They modulate gene expression by interacting with other TFs or binding to promoter sequences of downstream genes, thereby enhancing or suppressing transcription

It offers intensive therapeutic effects, including a powerful immune boost, addressing chronic infections, oxidative stress, and systemic inflammation

While those medications target the GLP-1 (glucagon-like peptide-1) receptor, Tirzepatide is classified as a dual agonist, meaning it acts on both the GLP-1 receptor and the GIP (glucose-dependent insulinotropic polypeptide) receptor

Previous studies on bone metabolism reported that phytoestrogens, including icariin and ginsenoside Rg1, influence the function of bone cells by activating GPER