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The data also showed reduced weight regain during treatment interruption, supporting the potential durability of peripheral CB1 inhibition when combined with GLP-1 therapy

In the NHS, Wegovy is typically prescribed through specialist weight management services for patients meeting specific NICE criteria (TA875), with treatment duration limits

Diagnostic tests may include full blood count, serum B12, holotranscobalamin (active B12), methylmalonic acid or homocysteine levels (if results are equivocal), and antiintrinsic factor antibodies when pernicious anaemia is suspected

Interestingly, a higher body mass index (BMI) appeared to have a protective effect against pancreatitis in some cases