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Varghese Jr., MD, MS, MBA, FACS, chief of general thoracic surgery at the University of Utah in Salt Lake City, offered a more cautious perspective: Its still too early right now, I think, for us to really know what the true incidence rate is around adverse events with GLP-1 receptor agonists. But per current guidelines, it appears limiting GLP-1RA intake before surgery could be unnecessary, easing concerns about balancing efficient surgery with patient safety

Effective doses: An ingredient only works if enough of it is included

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To investigate the genetic basis of this variability, here we conduct a genome-wide association study of self-reported weight loss and treatment-related side effects in 27,885 people following GLP1 receptor agonist therapy