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Disrupted intestinal permeability is closely associated with dysbiosis, and there is reason to think that repairing the mucosal barrier creates a more hospitable environment for a healthy microbial community

This program provides a temporary pathway for early access to GLP-1 coverage

The lead compound GDC-0810 showed robust activity in degrading ER- in MCF-7 cells, and demonstrated anti-cancer activity in both tamoxifen-sensitive and tamoxifen-resistant breast cancer models 129

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