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In recent years, natural polyphenols have shown great potential in combating cisplatin ototoxicity due to their powerful antioxidant, anti-inflammatory and anti-apoptotic properties.A variety of polyphenolic compounds, such as resveratrol, curcumin, quercetin, etc., can effectively attenuate the damage of cisplatin on Corti organs, spiral ganglion neurons and vascular striatum by scavenging free radicals, inhibiting the release of inflammatory factors, and regulating the expression of apoptosis-related proteins
doi: 10.1089/thy.2016.0397 39 BurchHBLahiriSBahnRSBarnesS
Lopes-Coelho F, Martins F, Hiplito A, Mendes C, Sequeira CO, Pires RF, et al
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