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Strengths include the utilization of clinically relevant bioimaging and biomarker data to assess change in bone health, along with the inclusion of men and persons identified as Hispanic, as both tend to be under-represented in weight loss trials ( 5 Conclusion In conclusion, results from this pilot trial demonstrate that 20 weeks of semaglutide combined with lifestyle counseling led to approximately 5% greater weight loss than that achieved with lifestyle counseling alone

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Finally, homocystinuria is easily detectable, as the symptoms include seizures and developmental delays