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Leptin levels decrease with semaglutide treatment as adipose tissue mass reduces, which is the expected physiological response
A secondary mechanism contributing to lean mass accretion beyond the direct anabolic effect
In vitro pSTAT3 response to leptin treatment HEK293 cells were transiently transfected with control DNA construct (pcDNA3.1) or DNA constructs expressing human GLP1R, human LEPR or both following standard Fugene method
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