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Treatment should be initiated and monitored by healthcare professionals experienced in weight management and obesity-related comorbidities

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Some studies have shown that in GLP-1R-overexpressing cells, PKA and AMPK are activated as the main downstream signaling molecules of GLP-1 (9-36), which is helpful for restoring cell vitality to meet the challenge of glutamic acid

Other studies have shown that a deficiency in NAD+ may result in cardiac disorders such as cardiac hypertrophy and fibrosis