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Other potential adverse effects of high dose and long-term glutathione supplementation include: Lightening of hair colour: A logically expected effect since hair colour is dependent on the amount and type of melanin which may be altered by glutathione supplementation

Increased risk of high-grade prostate cancer among infertile men

Under this background, in vitro models have been widely used in toxicity studies of TCMs because of their low cost, simple operation and Qualcomm screening ability

With this premise, in the 1970s, Bystrm proposed procarbazine for the treatment of PD, but subsequent studies did not reveal any objective benefit