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Because oral absorption may vary, supplements often include precursors such as N-acetylcysteine (NAC) or L-cysteine, which may support endogenous glutathione production
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Non-canonical NF-kappaB signaling pathway
For instance, a study in rats suggests that melatonin may counteract tau pathology by upregulating the activity of phosphatase 2A [114], an enzyme recognized for its role in dephosphorylating microtubule-associated protein tau [124]
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