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Abstract Introduction: Chronic rejection remains a major barrier to long-term survival after renal transplantation

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difficile (DSM 27543) was cultured in BHI medium supplemented with 5 g l 1 yeast extract, 0.1% (w/v) L-cysteine, 1 mg l 1 resazurine in an anaerobic (anaerobic: 5% H 2 , 10% CO 2 and 85% N 2 ) chamber (Whitley DG250 anaerobic working station)

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casei Zhang LDH: lactate dehydrogenase LDHA: lactate dehydrogenase A LDLR: low-density lipoprotein receptor LPS: lipopolysaccharide LTA: lipoteichoic acid LXR: liver X receptor MAMPs: microbial-associated molecular patterns MAPK: mitogen-activated protein kinase MCT4: monocarboxylate transporter 4 MDA: malondialdehyde MDMs: monocyte-derived macrophages miRNA: microRNA MR: mannose receptor NFD: normal fat diet NF-B: nuclear factor B NLRs: NOD-like receptors NO: nitric oxide OCR: oxygen consumption rate OXPHOS: oxidative phosphorylation PBMCs: peripheral blood mononuclear cells PCNA: Proliferating cell nuclear antigen PD: peritoneal dialysis Pdha1: pyruvate dehydrogenase 1 Pdhx: pyruvate dehydrogenase X Pdk2: pyruvate dehydrogenase kinases 2 Pdk4: pyruvate dehydrogenase kinases 4 PE: polyethylene PFK1: phosphofructokinase 1 PGN: peptidoglycan PKM2: pyruvate kinase M2 PMs: peritoneal macrophages PPAR-: peroxisome proliferator-activated receptor- PPAR: Peroxisome proliferator activator receptor delta PPP: pentose phosphate pathway PRRs: pattern recognition receptors RCT: reverse cholesterol transport RIG-I: retinoic acid-induced gene-1 RIPK2: serine/threonine protein kinase 2 ROS: reactive oxygen species RSV: respiratory syncytial virus S

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