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Hyperpigmentation: 4% niacinamide reduces melasma severity, and 5% formulations show tone improvement when paired with antioxidants and tranexamic acid
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It can be combined with microneedling or laser treatments: for example, a patient might receive GHK-Cu injections immediately after a laser session to enhance recovery
Neurological Symptoms Several Weeks to Months If you have tingling, numbness in your hands or feet, or balance problems caused by B12 deficiency, these symptoms take longer to improve
