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The mechanisms by which TMAO raises CV risk and accelerates atherosclerosis are not well understood, but studies have shown that TMAO arising from both choline and L-carnitine supplementation in mice may inhibit reverse cholesterol transport 35 and enhance foam cell formation in both arterial and peritoneal cavity 47

405 Modulating the gut microbiota through dietary interventions, probiotics, and fecal microbiota transplantation can positively influence neuronal health and alleviate neuropathic symptoms