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How researchers categorize peptides studied for metabolic and adipose-related outcomes Researchers typically sort fat-metabolism peptides into three broad mechanism-based groups: lipolytic peptides studied for direct interaction with fat cell receptors, growth-hormone secretagogues studied for their downstream effects on metabolic rate, and incretin-pathway peptides studied for their roles in appetite and glucose regulation
It says metformin remains first-line for type 2 diabetes and prediabetes, supported by decades of safety data and cardiovascular benefit evidence, while GLP-1 agonists have emerged as adjuncts for glycemic control, weight management and cardiovascular risk reduction
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