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Appl Microbiol Biotechnol 37:141146 Allocati N, Masulli M, Di Ilio C, Federici L (2018) Glutathione transferases: substrates, inhibitors and pro-drugs in cancer and neurodegenerative diseases

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In its invasive hyphal form, Candida penetrates the intestinal epithelium and releases more than 70 identified mycotoxins including acetaldehyde, gliotoxin, and candidalysin that trigger systemic inflammation, impair mitochondrial function, disrupt neurotransmitter synthesis, and compromise the integrity of the gut barrier, producing a multi-system clinical presentation that spans gastrointestinal, neurological, endocrine, dermatological, and immunological domains