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Estrs oxidativo La sobreexpresin de protenas relacionadas con la regulacin oxidativa y la proteccin celular frente al estrs oxidativo en el hgado de pacientes con PNALD (peroxiredosina-4, serotransferrina, glutatin S-transferasa P y Mn-superxido dismutasa) hacen pensar que el dao oxidativo es una de los mecanismos principales que explicaran el dao tisular en PNALD 51

59 Although some effects of GLP-1 RAs, particularly weight loss, are linked to direct effects of GLP-1 RAs in brain areas responsible for appetite, satiety, food behaviour and other central regulatory mechanisms, data regarding the potential impact of therapy on mental health among HF patients are lacking