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Notably, aging-related AE1 protein conformational changes result in the appearance of a senescent-specific antigen recognized by autologous antibodies [75]
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Symptoms of NAION can include: Sudden, mild to severe vision loss in one eye Blurred vision Color distortion Light sensitivity Dark area or shadow in vision Loss of peripheral vision Disc swelling (visible through eye exam) Potential risk factors of NAION include: Older than 50 years old Diabetes Hypertension High cholesterol Sleep apnea Some anatomical predispositions Medications like semaglutide (Ozempic) and sildenafil (Viagra) Because Ozempic is intended to help manage blood sugar levels in diabetic patients, changing blood sugar can lead to eye damage and vision changes
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