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GLP-1 receptor agonists have been shown in clinical studies to support meaningful and sustained weight loss when used alongside lifestyle changes such as improved diet, regular physical activity, and ongoing medical supervision
Cardiovascular safety may be assessed either before or after authorisation, depending on the indication and the risk profile of the medicine this is determined on a case-by-case basis and is not universally required pre-authorisation, particularly for obesity indications
Prescription antiemetics may be warranted for moderate to severe nausea
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