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Only 9.1% of its patent portfolio mentions GLP-1 agonists or semaglutide, and 2.3% specifically targets weight loss
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Glucagon-like peptide-1 receptor agonist attenuates autophagy to ameliorate pulmonary arterial hypertension through Drp1/NOX- and Atg-5/Atg-7/Beclin-1/LC3beta pathways
In patients with diabetes mellitus, the incidence of GI symptoms is significantly higher than in those without diabetes, especially in women with poor glycemic control, long-standing diabetes, or other diabetic complications, although the reported prevalence of DGE varies widely by region (Krishnasamy and Abell, 2018), with dysphagia (63%), gastroesophageal reflux (41%), early satiety or nausea (10%20%), constipation (60%), and diarrhea (20%) being especially prominent (Revicki et al., 2003
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