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Orforglipron is an oral GLP-1 medication eliminating the need for injections

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Interestingly, astrocytes often do not transition into this more damaging/senescent-like state unless microglia induce the switch through the release of cytokines like IL-1 and TNF (Herx et al., 2000

5,6 We did not evaluate the impact of discontinuing semaglutide or the potential side effects reported in previous trials, which include an elevated risk of developing thyroid cancer, gallbladder-related disorders, or gastrointestinal disorders