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These drugs can cross the BBB, reduce insulin resistance, stabilize mitochondrial function, and increase the survival and functional state of neurons
Common GI Side Effects Nausea, vomiting, diarrhea, constipation, abdominal pain, distension, dyspepsia, flatulence, and belching hit up to 50% of users during dose escalation
Some people find it helpful to take Ozempic before bed, while others feel better taking it in the morning
The higher rate with retatrutide 12 mg likely reflects the added glucagon receptor activity
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