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[hCG in non-trophoblastic oncology research models] [PMID: 17022551] Laboratory literature summary: [hCG in non-trophoblastic oncology research models]
A minor portion of the drug is metabolized in the liver by the cytochrome P450 enzymes (primarily CYP2E1) to the reactive and toxic APAP intermediate, N -acetyl-p-benzoquinone imine (NAPQI) (Patten et al
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283,284 In a small controlled trial, 23 healthy adults were given either 1,000 mg of guavirova, 100 mg of aspirin, or 500 mg of guavirova plus 50 mg of aspirin daily for five days
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