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The copper component serves as an essential cofactor for lysyl oxidase and lysyl hydroxylase, enzymes critical for proper collagen cross-linking
The amounts of total reduced and oxidized glutathione were quantified using a modified Tietze method by Adams ( Safety Measurements Any adverse event during the course of the study was monitored and reported to the study staff at week 6 (visit 5) or week 12 (visit 8) in the clinic or directly to the principal investigator throughout the study
The GHK-Cu spray delivers the copper tripeptide (glycyl-L-histidyl-L-lysine:copper) in a topical spray format designed for direct skin application providing a convenient delivery method for one of the most extensively studied regenerative peptides, with published data demonstrating modulation of over 4,000 human genes related to tissue remodeling, collagen synthesis, and wound healing
PLoS One 8 , e79016 (2013)
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