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Food hangs out in your stomach longer, which means you feel full, but also that big, heavy, or high-fat meals, and yes, cocktails, are more likely to result in nausea, reflux, or bloat
Two side effects were modestly more common than placebo headache (20% vs 12%) and lightheadedness (19% vs 12%) and these are almost entirely the diuretic effect (mild dehydration plus a slight blood-pressure drop)
These discussions are tailored to each patient and are grounded in practicality
Excluding the trial judged at high risk of bias for efficacy outcomes likewise did not materially change the estimate (SMD 1.32, 95% CI 2.33 to 0.31
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