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Our study indicates that upregulation of p53-pS15 and p16 maintains a persistent senescent microenvironment to promote cell cycle arrest and apoptosis resistance in keloid fibroblasts
These track inflammation and general health, not FOXO4-DRI activity directly
These studies reported subjective pain improvements and mobility increases, though they lacked appropriate placebo controls and blinding
Epidermal cells became more cuboidal, as is characteristic for stem cells
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