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However, the authors concluded that DMH LepR neurons are not essential for satiation or satiety, as the study found no significant increase in food intake or body weight following inhibition or disruption of these neurons [54]
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In a controlled trial of amphetamine (d- to l-enantiomer ratio of 3:1) in pediatric patients ages 13 to 17 years, mean weight change from baseline within the initial 4 weeks of therapy was -1.1 pounds and -2.8 pounds, respectively, for patients receiving 10 mg and 20 mg of amphetamine
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