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-HB could promote M2 macrophage polarization through the STAT6-dependent signaling pathway, and suppress M1 macrophage polarization through -hydroxybutyrylation of the STAT1 protein (167, 168)
The absorption of extracellular cystine is hindered by the decreased activity of system X C , which subsequently affects the synthesis of glutathione (GSH) [15]
However, standard oral glutathione supplements are often broken down by stomach acid before they can be absorbed
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