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For some people, especially those who cant absorb B12 properly through food or supplements (such as individuals with pernicious anaemia), regular B12 injections are necessary

Some people do have difficulties ingesting supplements, at which point a higher dosage can be prescribed (up to 10,000 mcg) by your doctor, in order to ensure you are getting the sufficient levels your body needs

However, for highly sensitive quantitative analysis, some advanced labs may account for it